Rofecoxib
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Scientific Name
Rofecoxib
Description of the Drug
Rofecoxib is a COX-2 inhibitor NSAID used to treat osteoarthritis, rheumatoid arthritis, acute pain, primary dysmenorrhea, and migraine attacks.
Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB00533
http://www.drugbank.ca/drugs/DB00533
Brand Name(s)
Vioxx
Company Owner(s)
Merck Research Laboratories Div Merck Co Inc
Mechanism(s) Of Action
| Target Name | Target Type | Action Type | Target ChEMBL ID |
|---|---|---|---|
| Cyclooxygenase-2 | SINGLE PROTEIN | INHIBITOR | CHEMBL230 |
Clinical Trial(s)
Unichem Links
| Atlas | rofecoxib | |
| SureChEMBL | SCHEMBL3050 | |
| PharmGKB | PA451268 | |
| DrugBank | DB00533 | |
| PubChem: Thomson Pharma | 14752370 | |
| PubChem | 5090 | |
| Mcule | MCULE-4806636118 | |
| LINCS | LSM-2482 | |
| Nikkaji | J1.041.252H | |
| PDBe | RCX | |
| BindingDB | 22369 | |
| EPA CompTox Dashboard | DTXSID2023567 | |
| DrugCentral | 2397 | |
| Brenda | 8711 | 69449 |
| ChemicalBook | CB6327130 | |
| Guide to Pharmacology | 2893 | |
| rxnorm | ROFECOXIB | |
| PubChem: Drugs of the Future | 12014954 | |
| KEGG Ligand | C07590 | |
| ChEBI | 8887 | |
| ZINC | ZINC000000007455 |
