Pyrimethamine
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Scientific Name
Pyrimethamine
Description of the Drug
Pyrimethamine is an antiparasitic drug used in the prevention and treatment of toxoplasmosis and malaria.
Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB00205
http://www.drugbank.ca/drugs/DB00205
Brand Name(s)
Chloridin, Daraprim, Malacide
Company Owner(s)
Hoffmann La Roche Inc, Teva Pharmaceuticals Development Inc, Alvogen Inc, Cerovene Inc, Vyera Pharmaceuticals Llc
Mechanism(s) Of Action
| Target Name | Target Type | Action Type | Target ChEMBL ID |
|---|---|---|---|
| Dihydrofolate reductase | SINGLE PROTEIN | INHIBITOR | CHEMBL1939 |
Clinical Trial(s)
Unichem Links
| SureChEMBL | SCHEMBL25129 | ||
| PharmGKB | PA451193 | ||
| Human Metabolome Database | HMDB0014350 | ||
| DrugBank | DB00205 | ||
| PubChem: Thomson Pharma | 15221150 | ||
| PubChem | 4993 | ||
| LINCS | LSM-3967 | ||
| Nikkaji | J4.589F | ||
| PDBe | CP6 | ||
| BindingDB | 18512 | ||
| EPA CompTox Dashboard | DTXSID9021217 | ||
| DrugCentral | 2332 | ||
| Brenda | 761 | 239402 | 13930 |
| ChemicalBook | CB8461315 | ||
| Guide to Pharmacology | 4800 | ||
| rxnorm | DARAPRIM | PYRIMETHAMINE | |
| PubChem: Drugs of the Future | 22395175 | ||
| KEGG Ligand | C07391 | ||
| ChEBI | 8673 | ||
| ZINC | ZINC000000057464 |
