Propylthiouracil
Back to searchMolecule Structure
Scientific Name
Propylthiouracil
Description of the Drug
Propylthiouracil is a thiourea antithyroid agent used to treat hyperthyroidism.
Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB00550
http://www.drugbank.ca/drugs/DB00550
Brand Name(s)
Propacil, Propylthiouracil, Prothyran, Thyreostat
Company Owner(s)
Dava Pharmaceuticals Inc, Tablicaps Inc, Sun Pharmaceutical Industries Inc, Halsey Drug Co Inc, Watson Laboratories Inc, Abbott Laboratories Pharmaceutical Products Div, Chartwell Rx Sciences Llc, Eli Lilly And Co, Actavis Elizabeth Llc, Ani Pharmaceuticals Inc
Mechanism(s) Of Action
Target Name | Target Type | Action Type | Target ChEMBL ID |
---|---|---|---|
Thyroid peroxidase | SINGLE PROTEIN | INHIBITOR | CHEMBL1839 |
Type I iodothyronine deiodinase (Type-I 5′-deiodinase) (DIOI) (Type 1 DI) (5DI) | SINGLE PROTEIN | INHIBITOR | CHEMBL2019 |
Clinical Trial(s)
Unichem Links
Atlas | propylthiouracil | ||
SureChEMBL | SCHEMBL41239 | SCHEMBL17375339 | |
PharmGKB | PA451156 | ||
Human Metabolome Database | HMDB0014690 | ||
DrugBank | DB00550 | ||
PubChem: Thomson Pharma | 14772576 | ||
PubChem | 657298 | ||
Mcule | MCULE-9403710688 | ||
NMRShiftDB | 20096866 | ||
LINCS | LSM-5592 | ||
Nikkaji | J1.363C | ||
PDBe | 3CJ | ||
BindingDB | 50133597 | ||
EPA CompTox Dashboard | DTXSID5021209 | ||
DrugCentral | 2308 | ||
Brenda | 4773 | 151046 | 68962 |
ChemicalBook | CB9777662 | ||
Guide to Pharmacology | 6650 | ||
rxnorm | PROPYLTHIOURACIL | ||
KEGG Ligand | C07569 | ||
ChEBI | 8502 | ||
ZINC | ZINC000004640636 |