Propylthiouracil

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Molecule Structure

Scientific Name

Propylthiouracil

Description of the Drug

Propylthiouracil is a thiourea antithyroid agent used to treat hyperthyroidism.

Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB00550

Brand Name(s)

Propacil, Propylthiouracil, Prothyran, Thyreostat

Company Owner(s)

Dava Pharmaceuticals Inc, Tablicaps Inc, Sun Pharmaceutical Industries Inc, Halsey Drug Co Inc, Watson Laboratories Inc, Abbott Laboratories Pharmaceutical Products Div, Chartwell Rx Sciences Llc, Eli Lilly And Co, Actavis Elizabeth Llc, Ani Pharmaceuticals Inc

Mechanism(s) Of Action

Target Name Target Type Action Type Target ChEMBL ID
Thyroid peroxidase SINGLE PROTEIN INHIBITOR CHEMBL1839
Type I iodothyronine deiodinase (Type-I 5′-deiodinase) (DIOI) (Type 1 DI) (5DI) SINGLE PROTEIN INHIBITOR CHEMBL2019

Unichem Links

Atlas propylthiouracil
SureChEMBL SCHEMBL41239 SCHEMBL17375339
PharmGKB PA451156
Human Metabolome Database HMDB0014690
DrugBank DB00550
PubChem: Thomson Pharma 14772576
PubChem 657298
Mcule MCULE-9403710688
NMRShiftDB 20096866
LINCS LSM-5592
Nikkaji J1.363C
PDBe 3CJ
BindingDB 50133597
EPA CompTox Dashboard DTXSID5021209
DrugCentral 2308
Brenda 4773 151046 68962
ChemicalBook CB9777662
Guide to Pharmacology 6650
rxnorm PROPYLTHIOURACIL
KEGG Ligand C07569
ChEBI 8502
ZINC ZINC000004640636