Propafenone

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Molecule Structure

Scientific Name

Propafenone

Description of the Drug

Propafenone is a Class 1C antiarrhythmic agent used in the management of paroxysmal atrial fibrillation/flutter and ventricular arrhythmias.

Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB01182

Brand Name(s)

Not Available

Company Owner(s)

Nesher Pharmaceuticals Usa Llc, Sun Pharmaceutical Industries Inc, Watson Laboratories, Watson Laboratories Inc, Sinotherapeutics Inc, Twi Pharmaceuticals Inc, Upsher Smith Laboratories Llc, Aurobindo Pharma Ltd, Ani Pharmaceuticals Inc, Glenmark Pharmaceuticals Ltd

Mechanism(s) Of Action

Target Name Target Type Action Type Target ChEMBL ID
Beta-1 adrenergic receptor SINGLE PROTEIN ANTAGONIST CHEMBL213
Sodium channel alpha subunit PROTEIN FAMILY BLOCKER CHEMBL2331043
Beta-2 adrenergic receptor SINGLE PROTEIN ANTAGONIST CHEMBL210

Unichem Links

SureChEMBL SCHEMBL27865 SCHEMBL16730120
PharmGKB PA451131
Human Metabolome Database HMDB0015313
DrugBank DB01182
PubChem: Thomson Pharma 14900354
PubChem 4932
Mcule MCULE-8776872379
LINCS LSM-1416
Nikkaji J12.333A
BindingDB 50067133
EPA CompTox Dashboard DTXSID9045184
DrugCentral 2291
Brenda 122954 229819 229818
ChemicalBook CB2854418 CB2183169
Guide to Pharmacology 2561
rxnorm PROPAFENONE RYTHMOL PROPAFENONE HYDROCHLORIDE
KEGG Ligand C07381
ChEBI 63619