Prochlorperazine
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Scientific Name
Prochlorperazine
Description of the Drug
Prochlorperazine is a phenothiazine derivative used in the treatment of schizophrenia and anxiety and to relieve severe nausea and vomiting.
Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB00433
http://www.drugbank.ca/drugs/DB00433
Brand Name(s)
Compazine, Compro, Prochlorperazine, Stemetil eff
Company Owner(s)
Glaxosmithkline, Watson Laboratories Inc, Duramed Pharmaceuticals Inc Sub Barr Laboratories Inc, Mylan Pharmaceuticals Inc, Emcure Pharmaceuticals Ltd, Ivax Pharmaceuticals Inc Sub Teva Pharmaceuticals Usa, Novitium Pharma Llc, Able Laboratories Inc, Cosette Pharmaceuticals Inc, Wyeth Ayerst Laboratories
Mechanism(s) Of Action
| Target Name | Target Type | Action Type | Target ChEMBL ID |
|---|---|---|---|
| Dopamine D2 receptor | SINGLE PROTEIN | ANTAGONIST | CHEMBL217 |
Clinical Trial(s)
Unichem Links
| Atlas | prochlorperazine | ||||
| SureChEMBL | SCHEMBL18429 | ||||
| PharmGKB | PA451114 | ||||
| Human Metabolome Database | HMDB0014577 | ||||
| DrugBank | DB00433 | ||||
| PubChem: Thomson Pharma | 14828997 | ||||
| PubChem | 4917 | ||||
| LINCS | LSM-2436 | ||||
| Nikkaji | J1.386B | ||||
| PDBe | P77 | ||||
| BindingDB | 78434 | ||||
| EPA CompTox Dashboard | DTXSID7023514 | ||||
| DrugCentral | 2274 | ||||
| ChemicalBook | CB7352500 | ||||
| Guide to Pharmacology | 7279 | ||||
| rxnorm | COMPRO | COMPAZINE | PROCHLORPERAZINE EDISYLATE | PROCHLORPERAZINE | PROCHLORPERAZINE MALEATE |
| KEGG Ligand | C07403 | ||||
| ChEBI | 8435 | ||||
| ZINC | ZINC000019796018 |
