Pralsetinib

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Molecule Structure

Scientific Name

Pralsetinib

Description of the Drug

Pralsetinib is a RET receptor tyrosine kinase inhibitor for the treatment of metastatic RET-driven non-small cell lung cancer.

Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB15822

Brand Name(s)

Gavreto

Company Owner(s)

Genentech Inc

Mechanism(s) Of Action

Target Name Target Type Action Type Target ChEMBL ID
Coiled-coil domain-containing protein 6/Tyrosine-protein kinase receptor RET CHIMERIC PROTEIN INHIBITOR CHEMBL3430904
Kinesin-1 heavy chain/ Tyrosine-protein kinase receptor RET CHIMERIC PROTEIN INHIBITOR CHEMBL3430888
Tyrosine-protein kinase receptor RET SINGLE PROTEIN INHIBITOR CHEMBL2041

Unichem Links

SureChEMBL SCHEMBL18789229
DrugBank DB15822
Guide to Pharmacology 10033