Molecule Structure

Scientific Name

Ponatinib

Description of the Drug

Ponatinib is a kinase inhibitor used to treat patients with various types of chronic myeloid leukemia (CML).

Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB08901

Brand Name(s)

Iclusig

Company Owner(s)

Takeda Pharmaceuticals Usa Inc

Mechanism(s) Of Action

Target Name Target Type Action Type Target ChEMBL ID
Bcr/Abl fusion protein CHIMERIC PROTEIN INHIBITOR CHEMBL2096618

Unichem Links

SureChEMBL SCHEMBL589260
PharmGKB PA165980594
Human Metabolome Database HMDB0240214
DrugBank DB08901
PubChem: Thomson Pharma 49848164
PubChem 24826799
LINCS LSM-1151
Nikkaji J2.843.862A
PDBe 0LI
BindingDB 50322535
EPA CompTox Dashboard DTXSID50241426
DrugCentral 4716
Brenda 227977 213585
ChemicalBook CB12518324
Guide to Pharmacology 5890
rxnorm PONATINIB ICLUSIG PONATINIB HYDROCHLORIDE
PubChem: Drugs of the Future 136350016
ChEBI 78543
ZINC ZINC000036701290