Pitolisant

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Molecule Structure

Scientific Name

Pitolisant

Description of the Drug

Pitolisant is an antagonist and inverse agonist at the histamine H3 receptor that is used to treat narcolepsy in adults.

Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB11642

Brand Name(s)

Wakix, Wakix, europe

Company Owner(s)

Harmony Biosciences Llc

Mechanism(s) Of Action

Target Name Target Type Action Type Target ChEMBL ID
Histamine H3 receptor SINGLE PROTEIN INVERSE AGONIST CHEMBL264

Unichem Links

SureChEMBL SCHEMBL117648
Human Metabolome Database HMDB0256619
DrugBank DB11642
PubChem: Thomson Pharma 14922700
PubChem 9948102
Nikkaji J1.574.747A
BindingDB 50247053
DrugCentral 5048
ChemicalBook CB52563438
Guide to Pharmacology 8924
rxnorm PITOLISANT WAKIX PITOLISANT HYDROCHLORIDE
ChEBI 134709
ZINC ZINC000034045468