Pilocarpine
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Scientific Name
Pilocarpine
Description of the Drug
Pilocarpine is a muscarinic cholinergic agonist used on the eye to treat elevated intraocular pressure, various types of glaucoma, and to induce miosis. Also available orally to treat symptoms of dry mouth associated with Sjogren’s syndrome and radiotherapy.
Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB01085
http://www.drugbank.ca/drugs/DB01085
Brand Name(s)
Ocusert pilo, Ocusert pilo-20, Ocusert pilo-40
Company Owner(s)
Somerset Therapeutics Llc, Padagis Us Llc, Concordia Pharmaceuticals Inc, Amici Pharmaceuticals Llc, Alcon Laboratories Inc, Novartis Pharmaceuticals Corp, Aurobindo Pharma Ltd, Abbvie Inc, Amneal Eu Ltd, Lannett Co Inc
Mechanism(s) Of Action
Target Name | Target Type | Action Type | Target ChEMBL ID |
---|---|---|---|
Muscarinic acetylcholine receptor M1 | SINGLE PROTEIN | AGONIST | CHEMBL216 |
Muscarinic acetylcholine receptor M3 | SINGLE PROTEIN | AGONIST | CHEMBL245 |
Clinical Trial(s)
Unichem Links
SureChEMBL | SCHEMBL15146 | ||
PharmGKB | PA450962 | ||
Human Metabolome Database | HMDB0015217 | ||
DrugBank | DB01085 | ||
PubChem: Thomson Pharma | 15195684 | 15195683 | |
PubChem | 5910 | ||
Mcule | MCULE-2634151840 | ||
NMRShiftDB | 60022836 | ||
LINCS | LSM-5909 | ||
Nikkaji | J9.328I | ||
PDBe | 9PL | ||
BindingDB | 50008072 | ||
EPA CompTox Dashboard | DTXSID1021162 | ||
DrugCentral | 2166 | ||
Brenda | 13784 | ||
ChemicalBook | CB1756779 | ||
Guide to Pharmacology | 305 | ||
rxnorm | PILOCARPINE NITRATE | PILOCARPINE HYDROCHLORIDE | PILOCARPINE |
KEGG Ligand | C07474 | ||
ChEBI | 8207 | ||
ZINC | ZINC000000075008 |