Pilocarpine

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Molecule Structure

Scientific Name

Pilocarpine

Description of the Drug

Pilocarpine is a muscarinic cholinergic agonist used on the eye to treat elevated intraocular pressure, various types of glaucoma, and to induce miosis. Also available orally to treat symptoms of dry mouth associated with Sjogren’s syndrome and radiotherapy.

Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB01085

Brand Name(s)

Ocusert pilo, Ocusert pilo-20, Ocusert pilo-40

Company Owner(s)

Somerset Therapeutics Llc, Padagis Us Llc, Concordia Pharmaceuticals Inc, Amici Pharmaceuticals Llc, Alcon Laboratories Inc, Novartis Pharmaceuticals Corp, Aurobindo Pharma Ltd, Abbvie Inc, Amneal Eu Ltd, Lannett Co Inc

Mechanism(s) Of Action

Target Name Target Type Action Type Target ChEMBL ID
Muscarinic acetylcholine receptor M1 SINGLE PROTEIN AGONIST CHEMBL216
Muscarinic acetylcholine receptor M3 SINGLE PROTEIN AGONIST CHEMBL245

Unichem Links

SureChEMBL SCHEMBL15146
PharmGKB PA450962
Human Metabolome Database HMDB0015217
DrugBank DB01085
PubChem: Thomson Pharma 15195684 15195683
PubChem 5910
Mcule MCULE-2634151840
NMRShiftDB 60022836
LINCS LSM-5909
Nikkaji J9.328I
PDBe 9PL
BindingDB 50008072
EPA CompTox Dashboard DTXSID1021162
DrugCentral 2166
Brenda 13784
ChemicalBook CB1756779
Guide to Pharmacology 305
rxnorm PILOCARPINE NITRATE PILOCARPINE HYDROCHLORIDE PILOCARPINE
KEGG Ligand C07474
ChEBI 8207
ZINC ZINC000000075008