Pexidartinib
Back to searchMolecule Structure
Scientific Name
Pexidartinib
Description of the Drug
Pexidartinib is an antitumor agent that is used for the treatment of rare disease tenosynovial giant cell tumors (TGCT) by inhibiting colony-stimulating factor 1 and its receptor.
Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB12978
http://www.drugbank.ca/drugs/DB12978
Brand Name(s)
Not Available
Company Owner(s)
Daiichi Sankyo Inc
Mechanism(s) Of Action
Target Name | Target Type | Action Type | Target ChEMBL ID |
---|---|---|---|
Macrophage colony stimulating factor receptor | SINGLE PROTEIN | INHIBITOR | CHEMBL1844 |
Stem cell growth factor receptor | SINGLE PROTEIN | INHIBITOR | CHEMBL1936 |
Tyrosine-protein kinase receptor FLT3 | SINGLE PROTEIN | INHIBITOR | CHEMBL1974 |
Clinical Trial(s)
Unichem Links
SureChEMBL | SCHEMBL1267310 | ||
Human Metabolome Database | HMDB0256360 | ||
DrugBank | DB12978 | ||
PubChem: Thomson Pharma | 57245138 | ||
PubChem | 25151352 | ||
PDBe | P31 | ||
BindingDB | 50177716 | ||
DrugCentral | 5343 | ||
ChemicalBook | CB22742977 | ||
Guide to Pharmacology | 8710 | ||
rxnorm | PEXIDARTINIB HYDROCHLORIDE | PEXIDARTINIB | TURALIO |
ChEBI | 145373 | ||
ZINC | ZINC000115705166 |