Pexidartinib

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Molecule Structure

Scientific Name

Pexidartinib

Description of the Drug

Pexidartinib is an antitumor agent that is used for the treatment of rare disease tenosynovial giant cell tumors (TGCT) by inhibiting colony-stimulating factor 1 and its receptor.

Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB12978

Brand Name(s)

Not Available

Company Owner(s)

Daiichi Sankyo Inc

Mechanism(s) Of Action

Target Name Target Type Action Type Target ChEMBL ID
Macrophage colony stimulating factor receptor SINGLE PROTEIN INHIBITOR CHEMBL1844
Stem cell growth factor receptor SINGLE PROTEIN INHIBITOR CHEMBL1936
Tyrosine-protein kinase receptor FLT3 SINGLE PROTEIN INHIBITOR CHEMBL1974

Unichem Links

SureChEMBL SCHEMBL1267310
Human Metabolome Database HMDB0256360
DrugBank DB12978
PubChem: Thomson Pharma 57245138
PubChem 25151352
PDBe P31
BindingDB 50177716
DrugCentral 5343
ChemicalBook CB22742977
Guide to Pharmacology 8710
rxnorm PEXIDARTINIB HYDROCHLORIDE PEXIDARTINIB TURALIO
ChEBI 145373
ZINC ZINC000115705166