Perampanel

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Molecule Structure

Scientific Name

Perampanel

Description of the Drug

Perampanel is a non-competitive AMPA glutamate receptor antagonist used to treat partial-onset seizures with or without secondarily generalized seizures, and as adjunctive treatment of primary generalized tonic-clonic seizures in patients with epilepsy.

Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB08883

Brand Name(s)

Fycompa

Company Owner(s)

Accord Healthcare Inc, Eisai Inc, Teva Pharmaceuticals Usa Inc

Mechanism(s) Of Action

Target Name Target Type Action Type Target ChEMBL ID
Glutamate receptor ionotropic AMPA PROTEIN COMPLEX GROUP ANTAGONIST CHEMBL2096670

Unichem Links

SureChEMBL SCHEMBL194370
Human Metabolome Database HMDB0256305
DrugBank DB08883
PubChem: Thomson Pharma 14896254
PubChem 9924495
LINCS LSM-45792
Nikkaji J2.400.987D
PDBe 6ZP
BindingDB 50184410
EPA CompTox Dashboard DTXSID80191501
DrugCentral 4684
ChemicalBook CB12598797
Guide to Pharmacology 7050
rxnorm PERAMPANEL FYCOMPA
PubChem: Drugs of the Future 136349971
ChEBI 71013
ZINC ZINC000030691797