Pentoxifylline
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Scientific Name
Pentoxifylline
Description of the Drug
Pentoxifylline is a methylxanthine derivative used to treat intermittent claudication caused by chronic occlusive arterial disease of the limbs.
Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB00806
http://www.drugbank.ca/drugs/DB00806
Brand Name(s)
Neotren mr, Pentoxifylline, Pentoxil, Trental, Trental 100, Trental 400
Company Owner(s)
Apotex Inc, Pliva Inc An Indirect Wholly Owned Sub Of Teva Pharmaceuticals Usa Inc, Rising Pharma Holding Inc, Validus Pharmaceuticals Llc, Upsher Smith Laboratories Llc, Heritage Pharmaceuticals Inc Dba Avet Pharmaceuticals Inc, Ani Pharmaceuticals Inc, Valeant Pharmaceuticals North America Llc, Impax Laboratories Inc
Mechanism(s) Of Action
| Target Name | Target Type | Action Type | Target ChEMBL ID |
|---|---|---|---|
| 3′,5′-cyclic phosphodiesterase | PROTEIN FAMILY | INHIBITOR | CHEMBL2363066 |
| Adenosine A2 receptor | PROTEIN FAMILY | ANTAGONIST | CHEMBL2094257 |
Clinical Trial(s)
Unichem Links
| SureChEMBL | SCHEMBL34039 | |
| PharmGKB | PA450864 | |
| Human Metabolome Database | HMDB0014944 | |
| DrugBank | DB00806 | |
| PubChem: Thomson Pharma | 14799544 | |
| PubChem | 4740 | |
| Mcule | MCULE-9951939936 | |
| LINCS | LSM-3285 | |
| Nikkaji | J3.419C | |
| PDBe | PNX | |
| BindingDB | 10850 | |
| EPA CompTox Dashboard | DTXSID7023437 | |
| DrugCentral | 2099 | |
| Brenda | 209606 | 138805 |
| ChemicalBook | CB5721652 | |
| Guide to Pharmacology | 7095 | |
| rxnorm | PENTOXIFYLLINE | |
| PubChem: Drugs of the Future | 81044341 | |
| KEGG Ligand | C07424 | |
| ChEBI | 7986 | |
| ZINC | ZINC000001530776 |
