Pazopanib
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Scientific Name
Pazopanib
Description of the Drug
Pazopanib is an antineoplastic agent used in the treatment of advanced renal cell cancer and advanced soft tissue sarcoma in patients with prior chemotherapy.
Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB06589
http://www.drugbank.ca/drugs/DB06589
Brand Name(s)
Votrient
Company Owner(s)
Novartis Pharmaceuticals Corp
Mechanism(s) Of Action
| Target Name | Target Type | Action Type | Target ChEMBL ID |
|---|---|---|---|
| Stem cell growth factor receptor | SINGLE PROTEIN | INHIBITOR | CHEMBL1936 |
| Vascular endothelial growth factor receptor | PROTEIN FAMILY | INHIBITOR | CHEMBL2095227 |
| Platelet-derived growth factor receptor | PROTEIN COMPLEX | INHIBITOR | CHEMBL2095189 |
| Tyrosine-protein kinase LCK | SINGLE PROTEIN | INHIBITOR | CHEMBL258 |
| Fibroblast growth factor receptor 1 | SINGLE PROTEIN | INHIBITOR | CHEMBL3650 |
| Macrophage colony stimulating factor receptor | SINGLE PROTEIN | INHIBITOR | CHEMBL1844 |
| Fibroblast growth factor receptor 3 | SINGLE PROTEIN | INHIBITOR | CHEMBL2742 |
| Tyrosine-protein kinase ITK/TSK | SINGLE PROTEIN | INHIBITOR | CHEMBL2959 |
Clinical Trial(s)
Unichem Links
| SureChEMBL | SCHEMBL588608 | ||
| Human Metabolome Database | HMDB0256144 | ||
| DrugBank | DB06589 | ||
| PubChem: Thomson Pharma | 15102663 | ||
| PubChem | 10113978 | ||
| Mcule | MCULE-2193898201 | ||
| LINCS | LSM-1114 | ||
| Nikkaji | J2.417.435B | ||
| BindingDB | 26474 | ||
| EPA CompTox Dashboard | DTXSID8048733 | ||
| DrugCentral | 4118 | ||
| Brenda | 155472 | ||
| Guide to Pharmacology | 5698 | ||
| rxnorm | PAZOPANIB | VOTRIENT | PAZOPANIB HYDROCHLORIDE |
| ChEBI | 71219 | ||
| ZINC | ZINC000011617039 |
