Paroxetine

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Molecule Structure

Scientific Name

Paroxetine

Description of the Drug

Paroxetine is a selective serotonin reuptake inhibitor used to treat major depressive disorder, panic disorder, OCD, social phobia, generalized anxiety disorder, the vasomotor symptoms of menopause, and premenstrual dysphoric disorder.

Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB00715

Brand Name(s)

Paxil [as hydrochloride]

Company Owner(s)

Jubilant Generics Ltd, Sun Pharmaceutical Industries Inc, Mylan Pharmaceuticals Inc, Sebela Ireland Ltd, Zydus Pharmaceuticals Usa Inc, Novitium Pharma Llc, Prinston Pharmaceutical Inc, Sinotherapeutics Inc, Upsher Smith Laboratories Llc, Aurobindo Pharma Ltd

Mechanism(s) Of Action

Target Name Target Type Action Type Target ChEMBL ID
Serotonin transporter SINGLE PROTEIN INHIBITOR CHEMBL228

Unichem Links

Atlas paroxetine
SureChEMBL SCHEMBL27799
PharmGKB PA450801
Human Metabolome Database HMDB0014853
DrugBank DB00715
PubChem: Thomson Pharma 14924270 14850948
PubChem 43815
LINCS LSM-2843
Nikkaji J259.859K
PDBe 8PR
BindingDB 50331515 22416
EPA CompTox Dashboard DTXSID3023425
DrugCentral 2068
Brenda 75641 145977 36984
ChemicalBook CB5178021
Guide to Pharmacology 4790
rxnorm PAROXETINE HYDROCHLORIDE PAXIL PAROXETINE MESYLATE BRISDELLE PAROXETINE PEXEVA
PubChem: Drugs of the Future 12013591
KEGG Ligand C07415
ChEBI 7936
ZINC ZINC000000527386