Palonosetron

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Molecule Structure

Scientific Name

Palonosetron

Description of the Drug

Palonosetron is a serotonin antagonist used in the prophylaxis or management of vomiting that results from emetogenic chemotherapy, and for the management of postoperative nausea and vomiting.

Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB00377

Brand Name(s)

Not Available

Company Owner(s)

Virtus Pharmaceutical Inc, Cipla Ltd, Ingenus Pharmaceuticals Llc, Fresenius Kabi Usa Llc, Sandoz Inc, Sagent Pharmaceuticals Inc, Hospira Inc, Accord Healthcare Inc, Eugia Pharma Specialities Ltd, Dr Reddys Laboratories Ltd

Mechanism(s) Of Action

Target Name Target Type Action Type Target ChEMBL ID
Serotonin 3a (5-HT3a) receptor SINGLE PROTEIN ANTAGONIST CHEMBL1899

Unichem Links

SureChEMBL SCHEMBL3746
DrugBank DB00377
PubChem: Thomson Pharma 14775945 16060983
PubChem 6337614
LINCS LSM-5266
Nikkaji J632.622F
PDBe O7B
BindingDB 50417287
EPA CompTox Dashboard DTXSID5048342
DrugCentral 2046
ChemicalBook CB7257940 CB32131051
Guide to Pharmacology 7486
rxnorm PALONOSETRON HYDROCHLORIDE PALONOSETRON AUROTHIOGLUCOSE ALOXI
ChEBI 85161
ZINC ZINC000003795819