Palbociclib

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Molecule Structure

Scientific Name

Palbociclib

Description of the Drug

Palbociclib is an endocrine-based chemotherapeutic agent used in combination with other antineoplastic agents to treat HER2-negative and HR-positive advanced or metastatic breast cancer.

Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB09073

Brand Name(s)

Ibrance

Company Owner(s)

Pfizer Inc

Mechanism(s) Of Action

Target Name Target Type Action Type Target ChEMBL ID
CDK6/cyclin D1 PROTEIN COMPLEX INHIBITOR CHEMBL2111455
Cyclin-dependent kinase 4/cyclin D1 PROTEIN COMPLEX INHIBITOR CHEMBL1907601

Unichem Links

SureChEMBL SCHEMBL462630
PharmGKB PA166153469
Human Metabolome Database HMDB0256084
DrugBank DB09073
PubChem: Thomson Pharma 14808444
PubChem 5330286
LINCS LSM-1071
Nikkaji J3.007.984A
PDBe LQQ
BindingDB 6309
DrugCentral 4941
Brenda 213642 213667
ChemicalBook CB62464897
Guide to Pharmacology 7380
rxnorm PALBOCICLIB IBRANCE
PubChem: Drugs of the Future 12015755
ChEBI 85993
ZINC ZINC000003938686