Paclitaxel
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Scientific Name
Paclitaxel
Description of the Drug
Paclitaxel is a taxoid chemotherapeutic agent used as first-line and subsequent therapy for the treatment of advanced carcinoma of the ovary, and other various cancers including breast and lung cancer.
Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB01229
http://www.drugbank.ca/drugs/DB01229
Brand Name(s)
Abraxane, Pacitaxel, Paclitaxel, Paxene, Taxol, Taxol 100
Company Owner(s)
Abraxis Bioscience Llc, Fresenius Kabi Usa Llc, Msn Laboratories Private Ltd, Mylan Laboratories Ltd, Sandoz Inc, Hospira Inc, Hq Specialty Pharma Corp, Actavis Totowa Llc, Gland Pharma Ltd, Pliva Lachema As
Mechanism(s) Of Action
Target Name | Target Type | Action Type | Target ChEMBL ID |
---|---|---|---|
Tubulin | PROTEIN COMPLEX GROUP | INHIBITOR | CHEMBL2095182 |
Clinical Trial(s)
Unichem Links
SureChEMBL | SCHEMBL3976 | |||||
PharmGKB | PA450761 | |||||
Human Metabolome Database | HMDB0015360 | |||||
DrugBank | DB01229 | |||||
PubChem: Thomson Pharma | 14767269 | 14840887 | ||||
PubChem | 36314 | |||||
NMRShiftDB | 60021370 | |||||
LINCS | LSM-6346 | |||||
Nikkaji | J17.834I | |||||
PDBe | TA1 | |||||
BindingDB | 50001839 | |||||
EPA CompTox Dashboard | DTXSID9023413 | |||||
DrugCentral | 2044 | |||||
Metabolights | MTBLC45863 | |||||
Brenda | 8756 | 16457 | 230123 | 3120 | 230124 | 69683 |
Rhea | 45863 | |||||
ChemicalBook | CB3273425 | |||||
Guide to Pharmacology | 2770 | |||||
rxnorm | PACLITAXEL | ABRAXANE | PACLITAXEL PROTEIN-BOUND | |||
PubChem: Drugs of the Future | 12013494 | |||||
ChEBI | 45863 | |||||
ZINC | ZINC000096006020 |