Ondansetron

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Molecule Structure

Scientific Name

Ondansetron

Description of the Drug

Ondansetron is a serotonin 5-HT3 receptor antagonist used to prevent nausea and vomiting in cancer chemotherapy and postoperatively.

Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB00904

Brand Name(s)

Ondansetron, Zofran, Zofran odt, Zuplenz

Company Owner(s)

Glaxosmithkline, Claris Pharmaservices, Nesher Pharmaceuticals Usa Llc, American Regent Inc, Aquestive Therapeutics Inc, Mylan Pharmaceuticals Inc, Novartis Pharmaceuticals Corp, Atlantide Pharmaceuticals Ag, Emcure Pharmaceuticals Ltd, Rising Pharma Holdings Inc

Mechanism(s) Of Action

Target Name Target Type Action Type Target ChEMBL ID
Serotonin 3a (5-HT3a) receptor SINGLE PROTEIN ANTAGONIST CHEMBL1899

Unichem Links

SureChEMBL SCHEMBL4542
PharmGKB PA450705
Human Metabolome Database HMDB0005035
DrugBank DB00904
PubChem: Thomson Pharma 14873468
PubChem 4595
Mcule MCULE-9438746800
LINCS LSM-1375
Nikkaji J245.610I
PDBe S87
BindingDB 85330
EPA CompTox Dashboard DTXSID8023393
DrugCentral 1992
Brenda 122952
ChemicalBook CB6340203 CB9340204
Guide to Pharmacology 2290
rxnorm ONDANSETRON ZOFRAN ONDANSETRON HYDROCHLORIDE ZUPLENZ
KEGG Ligand C07325
ChEBI 7773