Olanzapine

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Molecule Structure

Scientific Name

Olanzapine

Description of the Drug

Olanzapine is an antipsychotic drug used in the management of schizophrenia, bipolar 1 disorder, and agitation associated with these disorders.

Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB00334

Brand Name(s)

Arkolamyl, Olanzapine, Zalasta, Zyprexa, Zyprexa zydis

Company Owner(s)

Sunshine Lake Pharma Co Ltd, Alkem Laboratories Ltd, Jubilant Generics Ltd, Macleods Pharmaceuticals Ltd, Eli Lilly Co, American Regent Inc, Mylan Pharmaceuticals Inc, Hec Pharm Usa Inc, Zydus Pharmaceuticals Usa Inc, Torrent Pharmaceuticals Ltd

Mechanism(s) Of Action

Target Name Target Type Action Type Target ChEMBL ID
D2-like dopamine receptor PROTEIN FAMILY ANTAGONIST CHEMBL2331075
Serotonin 2a (5-HT2a) receptor SINGLE PROTEIN ANTAGONIST CHEMBL224
Serotonin 2c (5-HT2c) receptor SINGLE PROTEIN ANTAGONIST CHEMBL225

Unichem Links

Atlas olanzapine
SureChEMBL SCHEMBL28763
Human Metabolome Database HMDB0005012
DrugBank DB00334
PubChem: Thomson Pharma 14923451
PubChem 135398745
NMRShiftDB 10021706
LINCS LSM-5359
Nikkaji J489.991A
BindingDB 35254
EPA CompTox Dashboard DTXSID9023388
DrugCentral 1982
Brenda 7606
ChemicalBook CB04188690 CB6755515 CB34188691 CB64188692 CB52743465
rxnorm OLANZAPINE PAMOATE MONOHYDRATE OLANZAPINE OLANZAPINE PAMOATE ZYPREXA
PubChem: Drugs of the Future 12014657
KEGG Ligand C07322
ChEBI 7735
ZINC ZINC000052957434