Obeticholic Acid

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Molecule Structure

Scientific Name

Obeticholic Acid

Description of the Drug

Obeticholic acid is a bile acid analog and farnesoid X receptor agonist used to treat primary biliary cholangitis in adult patients with inadequate clinical response or intolerance to UDCA.

Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB05990

Brand Name(s)

Ocaliva

Company Owner(s)

Intercept Pharmaceuticals Inc

Mechanism(s) Of Action

Target Name Target Type Action Type Target ChEMBL ID
Bile acid receptor FXR SINGLE PROTEIN AGONIST CHEMBL2047

Unichem Links

SureChEMBL SCHEMBL715823
DrugBank DB05990
PubChem: Thomson Pharma 16101459 14880306
PubChem 447715
Nikkaji J2.007.345D
PDBe CHC
BindingDB 21675
EPA CompTox Dashboard DTXSID20196671
DrugCentral 5155
Guide to Pharmacology 3435
rxnorm OBETICHOLIC ACID OCALIVA
PubChem: Drugs of the Future 123055342
KEGG Ligand C15636
ChEBI 43602
ZINC ZINC000014164617