Nintedanib

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Molecule Structure

Scientific Name

Nintedanib

Description of the Drug

Nintedanib is a triple angiokinase inhibitor indicated for the treatment of idiopathic pulmonary fibrosis, systemic sclerosis-associated interstitial lung disease, and in combination with docetaxel for non-small cell lung cancer.

Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB09079

Brand Name(s)

Ofev, Vargatef

Company Owner(s)

Boehringer Ingelheim Pharmaceuticals Inc

Mechanism(s) Of Action

Target Name Target Type Action Type Target ChEMBL ID
Fibroblast growth factor receptor PROTEIN FAMILY INHIBITOR CHEMBL2095217
Platelet-derived growth factor receptor PROTEIN COMPLEX INHIBITOR CHEMBL2095189
Vascular endothelial growth factor receptor PROTEIN FAMILY INHIBITOR CHEMBL2095227

Unichem Links

SureChEMBL SCHEMBL431006
DrugBank DB09079
PubChem: Thomson Pharma 14836969
Nikkaji J2.815.614F
PDBe XIN
BindingDB 50026612
DrugCentral 4903
Brenda 247462
ChemicalBook CB72510401 CB92467147 CB92469909
Guide to Pharmacology 5936
rxnorm OFEV NINTEDANIB ESYLATE NINTEDANIB
PubChem: Drugs of the Future 99431587
ChEBI 85164
ZINC ZINC000100014909