Molecule Structure

Scientific Name

Neratinib

Description of the Drug

Neratinib is a protein kinase inhibitor used to treat breast cancer that over expresses the HER2 receptor.

Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB11828

Brand Name(s)

Not Available

Company Owner(s)

Puma Biotechnology Inc

Mechanism(s) Of Action

Target Name Target Type Action Type Target ChEMBL ID
Receptor protein-tyrosine kinase erbB-2 SINGLE PROTEIN INHIBITOR CHEMBL1824
Receptor protein-tyrosine kinase erbB-4 SINGLE PROTEIN INHIBITOR CHEMBL3009
Epidermal growth factor receptor erbB1 SINGLE PROTEIN INHIBITOR CHEMBL203

Unichem Links

SureChEMBL SCHEMBL571762
DrugBank DB11828
PubChem: Thomson Pharma 14886227
PubChem 9915743
LINCS LSM-42778
Nikkaji J2.688.659G
BindingDB 50161957
EPA CompTox Dashboard DTXSID70220132
DrugCentral 5252
Brenda 213554
ChemicalBook CB2855051
Guide to Pharmacology 5686
rxnorm NERLYNX NERATINIB NERATINIB MALEATE
PubChem: Drugs of the Future 123055351
ChEBI 61397
ZINC ZINC000003916214