Naloxone
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Scientific Name
Naloxone
Description of the Drug
Naloxone is an opioid receptor antagonist used to rapidly reverse an opioid overdose. Also included in some drug formulations as an abuse deterrent to prevent injection.
Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB01183
http://www.drugbank.ca/drugs/DB01183
Brand Name(s)
Nalone, Narcan, Narcanti
Company Owner(s)
Igi Laboratories Inc, Alkem Laboratories Ltd, Solopak Medical Products Inc, Watson Laboratories Inc, Dr Reddys Laboratories Sa, Rhodes Pharmaceuticals Lp, Amneal Pharmaceuticals Of New York Llc, Wes Pharma Inc, Akorn Operating Co Llc, Hikma Pharmaceuticals International Ltd
Mechanism(s) Of Action
Target Name | Target Type | Action Type | Target ChEMBL ID |
---|---|---|---|
Opioid receptors; mu/kappa/delta | PROTEIN FAMILY | ANTAGONIST | CHEMBL2095181 |
Clinical Trial(s)
Unichem Links
SureChEMBL | SCHEMBL34284 | ||||
PharmGKB | PA450586 | ||||
Human Metabolome Database | HMDB0015314 | ||||
DrugBank | DB01183 | ||||
PubChem: Thomson Pharma | 16463984 | 14777335 | 14924176 | ||
PubChem | 5284596 | ||||
Mcule | MCULE-1335589007 | ||||
NMRShiftDB | 60067801 | ||||
LINCS | LSM-3504 | ||||
Nikkaji | J5.894G | ||||
BindingDB | 50000788 | 54795 | |||
EPA CompTox Dashboard | DTXSID8023349 | ||||
DrugCentral | 1878 | ||||
Metabolights | MTBLC7459 | ||||
Brenda | 6568 | 36382 | |||
ChemicalBook | CB5728727 | ||||
Guide to Pharmacology | 1638 | 1676 | |||
rxnorm | NALOXONE HYDROCHLORIDE | NALOXONE | NARCAN | EVZIO | SUBOXONE |
KEGG Ligand | C07252 | ||||
ChEBI | 7459 | ||||
ZINC | ZINC000000389747 |