Mitotane
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Scientific Name
Mitotane
Description of the Drug
Mitotane is an adrenal cortex inhibitor used to treat adrenocortical tumors and Cushing’s syndrome.
Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB00648
http://www.drugbank.ca/drugs/DB00648
Brand Name(s)
Lysodren, Opddd
Company Owner(s)
Hra Pharma Rare Diseases
Mechanism(s) Of Action
Target Name | Target Type | Action Type | Target ChEMBL ID |
---|---|---|---|
Cytochrome P450 11B1 | SINGLE PROTEIN | INHIBITOR | CHEMBL1908 |
Cytochrome P450 11A1 | SINGLE PROTEIN | INHIBITOR | CHEMBL2033 |
Clinical Trial(s)
Unichem Links
SureChEMBL | SCHEMBL4040 | |
PharmGKB | PA164746157 | |
Human Metabolome Database | HMDB0014786 | |
DrugBank | DB00648 | |
PubChem: Thomson Pharma | 14801378 | |
PubChem | 4211 | |
Mcule | MCULE-2068358149 | |
LINCS | LSM-1451 | |
Nikkaji | J1.366H | |
BindingDB | 50239991 | |
EPA CompTox Dashboard | DTXSID9020372 | |
DrugCentral | 1820 | |
Brenda | 55840 | |
ChemicalBook | CB0392321 | |
Guide to Pharmacology | 6957 | |
rxnorm | LYSODREN | MITOTANE |
ChEBI | 6954 |