Molecule Structure

Scientific Name

Mitotane

Description of the Drug

Mitotane is an adrenal cortex inhibitor used to treat adrenocortical tumors and Cushing’s syndrome.

Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB00648

Brand Name(s)

Lysodren, Opddd

Company Owner(s)

Hra Pharma Rare Diseases

Mechanism(s) Of Action

Target Name Target Type Action Type Target ChEMBL ID
Cytochrome P450 11B1 SINGLE PROTEIN INHIBITOR CHEMBL1908
Cytochrome P450 11A1 SINGLE PROTEIN INHIBITOR CHEMBL2033

Unichem Links

SureChEMBL SCHEMBL4040
PharmGKB PA164746157
Human Metabolome Database HMDB0014786
DrugBank DB00648
PubChem: Thomson Pharma 14801378
PubChem 4211
Mcule MCULE-2068358149
LINCS LSM-1451
Nikkaji J1.366H
BindingDB 50239991
EPA CompTox Dashboard DTXSID9020372
DrugCentral 1820
Brenda 55840
ChemicalBook CB0392321
Guide to Pharmacology 6957
rxnorm LYSODREN MITOTANE
ChEBI 6954