Mirtazapine

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Molecule Structure

Scientific Name

Mirtazapine

Description of the Drug

Mirtazapine is a tetracyclic antidepressant used in the treatment of major depression and is used off-label as a drug for insomnia and to increase appetite.

Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB00370

Brand Name(s)

Mirtazapine, Remeron, Remeron soltab, Zispin

Company Owner(s)

Teva Pharmaceuticals Usa Inc, Ivax Pharmaceuticals Inc Sub Teva Pharmaceuticals Usa, Apotex Inc Etobicoke Site, Sun Pharmaceutical Industries Inc, Actavis Laboratories Fl Inc, Watson Laboratories Inc, Upsher Smith Laboratories Llc, Roxane Laboratories Inc, Actavis Elizabeth Llc, Aurobindo Pharma Ltd

Mechanism(s) Of Action

Target Name Target Type Action Type Target ChEMBL ID
Adrenergic receptor alpha-2 PROTEIN FAMILY ANTAGONIST CHEMBL2095158
Serotonin 2a (5-HT2a) receptor SINGLE PROTEIN ANTAGONIST CHEMBL224
Serotonin 2c (5-HT2c) receptor SINGLE PROTEIN ANTAGONIST CHEMBL225

Unichem Links

SureChEMBL SCHEMBL35408
PharmGKB PA450522
Human Metabolome Database HMDB0014514
DrugBank DB00370
PubChem: Thomson Pharma 14848184
PubChem 4205
Mcule MCULE-1174883554
LINCS LSM-1706
Nikkaji J22.953I
BindingDB 50115644
EPA CompTox Dashboard DTXSID0023325
DrugCentral 1816
Brenda 210369
ChemicalBook CB7463387 CB0463388
Guide to Pharmacology 7241
rxnorm REMERON MIRATAZ MIRTAZAPINE
PubChem: Drugs of the Future 12013213
KEGG Ligand C07570
ChEBI 6950