Metoclopramide
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Scientific Name
Metoclopramide
Description of the Drug
Metoclopramide is an antiemetic agent and dopamine D2 antagonist used in the treatment of gastroesophageal reflux disease, prevention of nausea and vomiting, and to stimulate gastric emptying.
Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB01233
http://www.drugbank.ca/drugs/DB01233
Brand Name(s)
Not Available
Company Owner(s)
Schering Corp Sub Schering Plough Corp, Sun Pharmaceutical Industries Inc, Halsey Drug Co Inc, Watson Laboratories Inc, Actavis Mid Atlantic Llc, Hospira Worldwide, Inc, Emcure Pharmaceuticals Ltd, Impax Laboratories Inc, Meda Pharmaceuticals Inc, Bedford Laboratories Div Ben Venue Laboratories Inc
Mechanism(s) Of Action
| Target Name | Target Type | Action Type | Target ChEMBL ID |
|---|---|---|---|
| Dopamine D2 receptor | SINGLE PROTEIN | ANTAGONIST | CHEMBL217 |
| Serotonin 3a (5-HT3a) receptor | SINGLE PROTEIN | ANTAGONIST | CHEMBL1899 |
| Serotonin 4 (5-HT4) receptor | SINGLE PROTEIN | AGONIST | CHEMBL1875 |
Clinical Trial(s)
Unichem Links
| SureChEMBL | SCHEMBL18629 | ||
| PharmGKB | PA450475 | ||
| Human Metabolome Database | HMDB0015363 | ||
| DrugBank | DB01233 | ||
| PubChem: Thomson Pharma | 14873753 | ||
| PubChem | 4168 | ||
| Mcule | MCULE-8566255889 | ||
| LINCS | LSM-3689 | ||
| Nikkaji | J2.037K | ||
| BindingDB | 48320 | ||
| EPA CompTox Dashboard | DTXSID6045169 | ||
| DrugCentral | 1782 | ||
| Brenda | 31546 | 41127 | |
| Guide to Pharmacology | 241 | ||
| rxnorm | METOCLOPRAMIDE | REGLAN | METOCLOPRAMIDE HYDROCHLORIDE |
| KEGG Ligand | C07868 | ||
| ChEBI | 107736 | ||
| ZINC | ZINC000001530716 |
