Methyldopa
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Scientific Name
Methyldopa
Description of the Drug
Methyldopa is a centrally-acting alpha-2 adrenergic agonist used to manage hypertension alone or in combination with hydrochlorothiazide, and to treat hypertensive crises.
Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB00968
http://www.drugbank.ca/drugs/DB00968
Brand Name(s)
Aldomet, Dopamet, Lederdopa, Medomet, Metalpha 250, Metalpha 500, Methyldopa
Company Owner(s)
Dava Pharmaceuticals Inc, Sun Pharmaceutical Industries Inc, Halsey Drug Co Inc, Watson Laboratories Inc, Merck And Co Inc, Mylan Pharmaceuticals Inc, Purepac Pharmaceutical Co, Ivax Pharmaceuticals Inc Sub Teva Pharmaceuticals Usa, Rising Pharma Holdings Inc, Teva Pharmaceuticals Usa Inc
Mechanism(s) Of Action
| Target Name | Target Type | Action Type | Target ChEMBL ID |
|---|---|---|---|
| Adrenergic receptor alpha-2 | PROTEIN FAMILY | AGONIST | CHEMBL2095158 |
Clinical Trial(s)
Unichem Links
| Atlas | methyldopa | |||
| SureChEMBL | SCHEMBL34003 | |||
| PharmGKB | PA450453 | |||
| Human Metabolome Database | HMDB0011754 | |||
| DrugBank | DB00968 | |||
| PubChem: Thomson Pharma | 14748911 | 163489324 | ||
| PubChem | 38853 | 6919173 | ||
| Mcule | MCULE-8885874119 | |||
| NMRShiftDB | 80004369 | |||
| LINCS | LSM-5596 | |||
| Nikkaji | J9.247I | |||
| BindingDB | 48449 | |||
| EPA CompTox Dashboard | DTXSID5023295 | |||
| DrugCentral | 1762 | |||
| Metabolights | MTBLC61058 | |||
| Brenda | 21855 | 96125 | 45673 | 155827 |
| ChemicalBook | CB2723064 | CB4277127 | ||
| Guide to Pharmacology | 5217 | |||
| rxnorm | METHYLDOPA | METHYLDOPA ANHYDROUS | ||
| KEGG Ligand | C07194 | |||
| ChEBI | 61058 | |||
| ZINC | ZINC000000020255 |
