Methimazole
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Scientific Name
Methimazole
Description of the Drug
Methimazole is a thionamide antithyroid agent that inhibits the actions of thyroid peroxidase, leading to a reduction in thyroid hormone synthesis and amelioration of hyperthyroidism.
Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB00763
http://www.drugbank.ca/drugs/DB00763
Brand Name(s)
Favistan, Methimazole, Tapazole
Company Owner(s)
King Pharmaceuticals Llc, Sun Pharmaceutical Industries Inc, Chartwell Rx Sciences Llc, Biopharm Discovery Llc, Discovery Therapeutics Llc, King Pharmaceuticals Inc, Mylan Pharmaceuticals Inc, Heritage Pharma Labs Inc, Rising Pharma Holdings Inc
Mechanism(s) Of Action
| Target Name | Target Type | Action Type | Target ChEMBL ID |
|---|---|---|---|
| Thyroid peroxidase | SINGLE PROTEIN | INHIBITOR | CHEMBL1839 |
Clinical Trial(s)
Unichem Links
| Atlas | methimazole | ||||||
| SureChEMBL | SCHEMBL41647 | ||||||
| PharmGKB | PA450422 | ||||||
| Human Metabolome Database | HMDB0014901 | ||||||
| DrugBank | DB00763 | ||||||
| PubChem: Thomson Pharma | 15194357 | 15297082 | |||||
| PubChem | 1349907 | ||||||
| Mcule | MCULE-9902292741 | ||||||
| LINCS | LSM-5646 | ||||||
| Nikkaji | J1.400A | ||||||
| PDBe | MMZ | ||||||
| BindingDB | 50241361 | ||||||
| EPA CompTox Dashboard | DTXSID4020820 | ||||||
| DrugCentral | 1745 | ||||||
| Brenda | 30541 | 90546 | 1144 | 104592 | 42919 | 90547 | 32678 |
| ChemicalBook | CB9220870 | ||||||
| Guide to Pharmacology | 6649 | ||||||
| rxnorm | TAPAZOLE | METHIMAZOLE | |||||
| KEGG Ligand | C07190 | ||||||
| ChEBI | 50673 | ||||||
| ZINC | ZINC000001187543 |
