Metformin
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Scientific Name
Metformin
Description of the Drug
Metformin is a biguanide antihyperglycemic used in conjunction with diet and exercise for glycemic control in type 2 diabetes mellitus. It is also used off-label for insulin resistance in polycystic ovary syndrome (PCOS).
Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB00331
http://www.drugbank.ca/drugs/DB00331
Brand Name(s)
Not Available
Company Owner(s)
Sunshine Lake Pharma Co Ltd, Alkem Laboratories Ltd, Bristol Myers Squibb, Takeda Pharmaceuticals Usa Inc, Sun Pharmaceutical Industries Inc, Macleods Pharmaceuticals Ltd, Watson Laboratories Inc, Laurus Labs Ltd, Yichang Humanwell Pharmaceutical Co Ltd, Mylan Pharmaceuticals Inc
Mechanism(s) Of Action
Target Name | Target Type | Action Type | Target ChEMBL ID |
---|---|---|---|
Mitochondrial glycerol-3-phosphate dehydrogenase | SINGLE PROTEIN | INHIBITOR | CHEMBL3391681 |
Mitochondrial complex I (NADH dehydrogenase) | PROTEIN COMPLEX | INHIBITOR | CHEMBL2363065 |
Clinical Trial(s)
Unichem Links
Atlas | metformin | ||||||
SureChEMBL | SCHEMBL8944 | ||||||
PharmGKB | PA450395 | ||||||
Human Metabolome Database | HMDB0001921 | ||||||
DrugBank | DB00331 | ||||||
PubChem: Thomson Pharma | 15297229 | ||||||
PubChem | 4091 | 155906370 | |||||
Mcule | MCULE-7393156510 | ||||||
LINCS | LSM-4730 | ||||||
Nikkaji | J9.463C | ||||||
PDBe | MF8 | ||||||
BindingDB | 57047 | 50229665 | |||||
EPA CompTox Dashboard | DTXSID2023270 | ||||||
DrugCentral | 1725 | ||||||
ChemicalBook | CB0506294 | CB22706988 | |||||
Guide to Pharmacology | 4779 | 4503 | |||||
rxnorm | GLUMETZA | METFORMIN | RIOMET | JANUMET | GLUCOPHAGE | METFORMIN HYDROCHLORIDE | FORTAMET |
KEGG Ligand | C07151 | ||||||
ChEBI | 6801 | ||||||
ZINC | ZINC000012859773 |