Mesalamine
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Scientific Name
Mesalamine
Description of the Drug
Mesalazine is an aminosalicylate drug used to treat mild to moderate active ulcerative colitis and also to maintain remission once achieved.
Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB00244
http://www.drugbank.ca/drugs/DB00244
Brand Name(s)
Apriso, Asacol, Asacol hd, Canasa, Coltec ec, Delzicol, Ipocol, Lialda, Mesalamine, Mesren mr, Mezavant xl, Octasa, Pentasa, Pentasa sr, Rowasa, Salofalk, Sfrowasa
Company Owner(s)
Alkem Laboratories Ltd, Takeda Pharmaceuticals Usa Inc, Actavis Mid Atlantic Llc, Mylan Pharmaceuticals Inc, Amneal Pharmaceuticals Llc, Zydus Pharmaceuticals Usa Inc, Allergan Sales Llc, Meda Pharmaceuticals Inc, Actavis Laboratories Fl Inc An Indirect Wholly Owned Sub Of Teva Pharmaceuticals Usa Inc, Teva Pharmaceuticals Usa Inc
Mechanism(s) Of Action
| Target Name | Target Type | Action Type | Target ChEMBL ID |
|---|---|---|---|
| Arachidonate 5-lipoxygenase | SINGLE PROTEIN | INHIBITOR | CHEMBL215 |
| Cyclooxygenase | PROTEIN FAMILY | INHIBITOR | CHEMBL2094253 |
| Peroxisome proliferator-activated receptor gamma | SINGLE PROTEIN | AGONIST | CHEMBL235 |
Clinical Trial(s)
Unichem Links
| Atlas | mesalazine | |||||||
| SureChEMBL | SCHEMBL18038934 | SCHEMBL31297 | ||||||
| PharmGKB | PA450384 | |||||||
| Human Metabolome Database | HMDB0014389 | |||||||
| DrugBank | DB00244 | |||||||
| PubChem: Thomson Pharma | 15170925 | |||||||
| PubChem | 4075 | |||||||
| Mcule | MCULE-5752745805 | |||||||
| NMRShiftDB | 20037775 | |||||||
| LINCS | LSM-5427 | |||||||
| Nikkaji | J32.511B | |||||||
| BindingDB | 60918 | |||||||
| EPA CompTox Dashboard | DTXSID5024506 | |||||||
| DrugCentral | 1710 | |||||||
| Brenda | 36968 | 3607 | 109764 | 256575 | 1817 | |||
| ChemicalBook | CB1480481 | |||||||
| Guide to Pharmacology | 2700 | |||||||
| rxnorm | MESALAMINE | APRISO | ROWASA | DELZICOL | PENTASA | CANASA | LIALDA | ASACOL |
| PubChem: Drugs of the Future | 12015286 | |||||||
| ChEBI | 6775 | |||||||
| ZINC | ZINC000000001688 |
