Melphalan
Back to search| Scientific Name: | Melphalan |
| Brand Name: | Alkeran, Evomela |
| Company Owner: | Not Available |
| Mechanism Of Action | Melphalan attaches alkyl groups to the N-7 position of guanine and N-3 position of adenine, leading to the formation of monoadducts, and DNA fragmenting when repair enzymes attempt to correct the error. |
| Description of the Drug: | Melphalan is an alkylating antineoplastic agent used for high-dose conditioning prior to hematopoietic stem cell transplant in patients with multiple myeloma. |
| Protein Data Bank: | Not Available |
Source: DrugBank Online – DrugBank.com. Retrieved 2023-01-23 from https://go.drugbank.com/drugs/DB01042
