Megestrol Acetate

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Molecule Structure

Scientific Name

Megestrol Acetate

Description of the Drug

Megestrol acetate is a progestin that is administered orally to treat anorexia and cachexia or serious unexplained weight loss and is also used as an antineoplastic agent to treat certain types of malignancy.

Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB00351

Brand Name(s)

Megace, Megace es, Megestrol acetate, Ovaban

Company Owner(s)

Usl Pharma Inc, Teva Pharmaceuticals Usa Inc, Wockhardt Bio Ag, Bristol Myers Squibb, Pharmaceutical Associates Inc, Endo Pharmaceuticals Inc, Twi Pharmaceuticals Inc, Barr Laboratories Inc, Teva Pharmaceuticals Usa, Strides Pharma Global Pte Ltd

Mechanism(s) Of Action

Target Name Target Type Action Type Target ChEMBL ID
Progesterone receptor SINGLE PROTEIN AGONIST CHEMBL208

Unichem Links

SureChEMBL SCHEMBL745
DrugBank DB00351
PubChem: Thomson Pharma 14756125 14853785
PubChem 11683
LINCS LSM-2441
Nikkaji J6.777F
BindingDB 50238674
EPA CompTox Dashboard DTXSID9040683
LipidMaps LMST02030118
DrugCentral 1667
Brenda 122895
ChemicalBook CB9434253
rxnorm MEGACE MEGESTROL ACETATE MEGESTROL
KEGG Ligand C08151
ChEBI 6723
ZINC ZINC000004097467