Meclofenamic acid

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Scientific Name: Meclofenamic acid
Brand Name: Not Available
Company Owner: Quantum pharmics ltd, American therapeutics inc, Barr laboratories inc, Mylan pharmaceuticals inc, Par pharmaceutical inc, Sandoz inc, Usl pharma inc, Vitarine pharmaceuticals inc, Watson laboratories inc, Parke davis div warner lambert co
Mechanism Of Action The mode of action, like that of other nonsteroidal anti-inflammatory agents, is not known. Therapeutic action does not result from pituitary-adrenal stimulation. In animal studies, meclofenamic acid was found to inhibit prostaglandin synthesis and to compete for binding at the prostaglandin receptor site. In vitro meclofenamic acid was found to be an inhibitor of human leukocyte 5-lipoxygenase activity. These properties may be responsible for the anti-inflammatory action of meclofenamic acid. There is no evidence that meclofenamic acid alters the course of the underlying disease.
Description of the Drug: Meclofenamic acid is an NSAID used to treat mild to moderate pain, primary dysmenorrhea, heavy menstrual blood loss, rheumatoid arthritis, and osteoarthritis.
Protein Data Bank:
Source: DrugBank Online – DrugBank.com. Retrieved 2023-01-23 from https://go.drugbank.com/drugs/DB00939