Maprotiline
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Scientific Name
Maprotiline
Description of the Drug
Maprotiline is a tetracyclic antidepressant used to treat depressive illness, major depressive disorder, bipolar disorder, and anxiety associated with depression.
Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB00934
http://www.drugbank.ca/drugs/DB00934
Brand Name(s)
Not Available
Company Owner(s)
American Therapeutics Inc, Watson Laboratories Inc, Rising Pharma Holding Inc, Mylan Pharmaceuticals Inc, Novartis Pharmaceuticals Corp, Heritage Pharma Labs Inc
Mechanism(s) Of Action
| Target Name | Target Type | Action Type | Target ChEMBL ID |
|---|---|---|---|
| Norepinephrine transporter | SINGLE PROTEIN | INHIBITOR | CHEMBL222 |
Clinical Trial(s)
Unichem Links
| SureChEMBL | SCHEMBL33993 | |
| PharmGKB | PA450322 | |
| Human Metabolome Database | HMDB0015069 | |
| DrugBank | DB00934 | |
| PubChem: Thomson Pharma | 14775197 | |
| PubChem | 4011 | |
| LINCS | LSM-2043 | |
| Nikkaji | J9.818C | |
| BindingDB | 50101973 | 35228 |
| EPA CompTox Dashboard | DTXSID7045029 | |
| DrugCentral | 1634 | |
| Brenda | 34575 | |
| Guide to Pharmacology | 2402 | |
| rxnorm | MAPROTILINE | MAPROTILINE HYDROCHLORIDE |
| KEGG Ligand | C07107 | |
| ChEBI | 6690 | |
| ZINC | ZINC000001530688 |
