Lovastatin
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Scientific Name
Lovastatin
Description of the Drug
Lovastatin is an HMG-CoA reductase inhibitor used to lower LDL cholesterol and reduce the risk of cardiovascular disease and associated conditions, including myocardial infarction and stroke.
Source: DrugBank Online – DrugBank.com. Retrieved 2023-02-07 from
http://www.drugbank.ca/drugs/DB00227
http://www.drugbank.ca/drugs/DB00227
Brand Name(s)
Altoprev, Lovastatin, Mevacor, Mevinacor, Mevinacor 10, Mevinacor 40
Company Owner(s)
Corepharma Llc, Mylan Pharmaceuticals Inc, Carlsbad Technology Inc, Abbvie Inc, Merck Research Laboratories Div Merck Co Inc, Actavis Elizabeth Llc, Sandoz Inc, Sun Pharmaceutical Industries Inc, Lupin Ltd, Covis Pharma Gmbh
Mechanism(s) Of Action
| Target Name | Target Type | Action Type | Target ChEMBL ID |
|---|---|---|---|
| HMG-CoA reductase | SINGLE PROTEIN | INHIBITOR | CHEMBL402 |
Clinical Trial(s)
Unichem Links
| SureChEMBL | SCHEMBL3136 | ||
| PharmGKB | PA450272 | ||
| Human Metabolome Database | HMDB0014372 | ||
| DrugBank | DB00227 | ||
| PubChem: Thomson Pharma | 14806053 | 14879393 | |
| PubChem | 53232 | ||
| Mcule | MCULE-7087866108 | MCULE-4740518260 | |
| LINCS | LSM-2189 | ||
| Nikkaji | J22.276C | ||
| PDBe | 803 | ||
| BindingDB | 34168 | ||
| EPA CompTox Dashboard | DTXSID5020784 | ||
| DrugCentral | 1612 | ||
| Metabolights | MTBLC40303 | ||
| Brenda | 111182 | 17608 | |
| Rhea | 40303 | ||
| Guide to Pharmacology | 2739 | ||
| GSRS | c79c0ca0-ed69-46fc-8f5b-c48bd2347ed3 | ||
| rxnorm | ALTOPREV | LOVASTATIN | MEVACOR |
| PubChem: Drugs of the Future | 12012664 | ||
| KEGG Ligand | C07074 | ||
| ChEBI | 40303 | ||
| NIH Clinical Collection | SAM002589963 | ||
| ZINC | ZINC000003812841 |
