Lovastatin

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Molecule Structure

Scientific Name

Lovastatin

Description of the Drug

Lovastatin is an HMG-CoA reductase inhibitor used to lower LDL cholesterol and reduce the risk of cardiovascular disease and associated conditions, including myocardial infarction and stroke.

Source: DrugBank Online – DrugBank.com. Retrieved 2023-02-07 from
http://www.drugbank.ca/drugs/DB00227

Brand Name(s)

Altoprev, Lovastatin, Mevacor, Mevinacor, Mevinacor 10, Mevinacor 40

Company Owner(s)

Corepharma Llc, Mylan Pharmaceuticals Inc, Carlsbad Technology Inc, Abbvie Inc, Merck Research Laboratories Div Merck Co Inc, Actavis Elizabeth Llc, Sandoz Inc, Sun Pharmaceutical Industries Inc, Lupin Ltd, Covis Pharma Gmbh

Mechanism(s) Of Action

Target Name Target Type Action Type Target ChEMBL ID
HMG-CoA reductase SINGLE PROTEIN INHIBITOR CHEMBL402

Unichem Links

SureChEMBL SCHEMBL3136
PharmGKB PA450272
Human Metabolome Database HMDB0014372
DrugBank DB00227
PubChem: Thomson Pharma 14806053 14879393
PubChem 53232
Mcule MCULE-7087866108 MCULE-4740518260
LINCS LSM-2189
Nikkaji J22.276C
PDBe 803
BindingDB 34168
EPA CompTox Dashboard DTXSID5020784
DrugCentral 1612
Metabolights MTBLC40303
Brenda 111182 17608
Rhea 40303
Guide to Pharmacology 2739
GSRS c79c0ca0-ed69-46fc-8f5b-c48bd2347ed3
rxnorm ALTOPREV LOVASTATIN MEVACOR
PubChem: Drugs of the Future 12012664
KEGG Ligand C07074
ChEBI 40303
NIH Clinical Collection SAM002589963
ZINC ZINC000003812841