Lorlatinib

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Molecule Structure

Scientific Name

Lorlatinib

Description of the Drug

Lorlatinib is an anaplastic lymphoma kinase inhibitor used to treat anaplastic lymphoma kinase positive metastatic non small cell lung cancer.

Source: DrugBank Online – DrugBank.com. Retrieved 2023-02-07 from
http://www.drugbank.ca/drugs/DB12130

Brand Name(s)

Lorbrena

Company Owner(s)

Pfizer Inc

Mechanism(s) Of Action

Target Name Target Type Action Type Target ChEMBL ID
EML4-ALK CHIMERIC PROTEIN INHIBITOR CHEMBL3883330
ALK tyrosine kinase receptor SINGLE PROTEIN INHIBITOR CHEMBL4247

Unichem Links

SureChEMBL SCHEMBL15261807
DrugBank DB12130
PubChem 71731823
Nikkaji J3.339.850F
PDBe 5P8
BindingDB 50018830
DrugCentral 5302
ChemicalBook CB02716543
Guide to Pharmacology 7476
GSRS fdc924ca-d8e6-4987-9c64-cc865c2e5ec7
rxnorm LORLATINIB LORBRENA
ChEBI 143117
ZINC ZINC000098208524