Lomitapide
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Scientific Name
Lomitapide
Description of the Drug
Lomitapide is a microsomal triglyceride transfer protein inhibitor used to lower cholesterol associated with homozygous familial hypercholesterolemia (HoFH), reducing risk of cardiovascular events such as myocardial infarction and stroke.
Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB08827
http://www.drugbank.ca/drugs/DB08827
Brand Name(s)
Lojuxta
Company Owner(s)
Amryt Pharmaceuticals Dac
Mechanism(s) Of Action
Target Name | Target Type | Action Type | Target ChEMBL ID |
---|---|---|---|
Microsomal triglyceride transfer protein | PROTEIN COMPLEX | INHIBITOR | CHEMBL2364681 |
Clinical Trial(s)
Unichem Links
SureChEMBL | SCHEMBL304604 | ||
Human Metabolome Database | HMDB0254156 | ||
DrugBank | DB08827 | ||
PubChem: Thomson Pharma | 14815135 | ||
PubChem | 9853053 | ||
LINCS | LSM-45564 | ||
Nikkaji | J1.390.273I | ||
BindingDB | 50098320 | ||
EPA CompTox Dashboard | DTXSID50171294 | ||
DrugCentral | 4721 | ||
ChemicalBook | CB62485047 | ||
Guide to Pharmacology | 7439 | ||
rxnorm | LOMITAPIDE MESYLATE | LOMITAPIDE | JUXTAPID |
ChEBI | 72297 | ||
ZINC | ZINC000027990463 |