Lomitapide

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Molecule Structure

Scientific Name

Lomitapide

Description of the Drug

Lomitapide is a microsomal triglyceride transfer protein inhibitor used to lower cholesterol associated with homozygous familial hypercholesterolemia (HoFH), reducing risk of cardiovascular events such as myocardial infarction and stroke.

Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB08827

Brand Name(s)

Lojuxta

Company Owner(s)

Amryt Pharmaceuticals Dac

Mechanism(s) Of Action

Target Name Target Type Action Type Target ChEMBL ID
Microsomal triglyceride transfer protein PROTEIN COMPLEX INHIBITOR CHEMBL2364681

Unichem Links

SureChEMBL SCHEMBL304604
Human Metabolome Database HMDB0254156
DrugBank DB08827
PubChem: Thomson Pharma 14815135
PubChem 9853053
LINCS LSM-45564
Nikkaji J1.390.273I
BindingDB 50098320
EPA CompTox Dashboard DTXSID50171294
DrugCentral 4721
ChemicalBook CB62485047
Guide to Pharmacology 7439
rxnorm LOMITAPIDE MESYLATE LOMITAPIDE JUXTAPID
ChEBI 72297
ZINC ZINC000027990463