Lofexidine
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Scientific Name
Lofexidine
Description of the Drug
Lofexidine is a centrally acting alpha2-adrenergic agonist used for the symptomatic treatment of acute opioid withdrawal syndrome to facilitate abrupt opioid discontinuation in adults.
Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB04948
http://www.drugbank.ca/drugs/DB04948
Brand Name(s)
Not Available
Company Owner(s)
Uswm Llc
Mechanism(s) Of Action
| Target Name | Target Type | Action Type | Target ChEMBL ID |
|---|---|---|---|
| Adrenergic receptor alpha-2 | PROTEIN FAMILY | AGONIST | CHEMBL2095158 |
Clinical Trial(s)
Unichem Links
| SureChEMBL | SCHEMBL48960 | ||
| PharmGKB | PA164744510 | ||
| Human Metabolome Database | HMDB0015606 | ||
| DrugBank | DB04948 | ||
| PubChem: Thomson Pharma | 14774610 | ||
| PubChem | 30668 | ||
| LINCS | LSM-4951 | ||
| Nikkaji | J20.359I | ||
| BindingDB | 50019646 | 85233 | |
| EPA CompTox Dashboard | DTXSID7023221 | ||
| DrugCentral | 1593 | ||
| Brenda | 217388 | ||
| ChemicalBook | CB3731949 | ||
| Guide to Pharmacology | 9868 | ||
| rxnorm | LUCEMYRA | LOFEXIDINE HYDROCHLORIDE | LOFEXIDINE |
| ChEBI | 51368 |
