Liothyronine

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Molecule Structure

Scientific Name

Liothyronine

Description of the Drug

Liothyronine is a thyroid hormone replacement therapy used to treat hypothyroidism, to suppress TSH, and to help in the diagnosis of hyperthyroidism.

Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB00279

Brand Name(s)

Cytomel, Tertroxin

Company Owner(s)

Parke Davis Div Warner Lambert Co, Teva Pharmaceuticals Usa Inc, King Pharmaceuticals Research And Development Llc, Sigmapharm Laboratories Llc, Par Sterile Products Llc, Sun Pharmaceutical Industries Ltd, Mayne Pharma Inc, Watson Laboratories Inc, Mylan Pharmaceuticals Inc, Xgen Pharmaceuticals Djb Inc

Mechanism(s) Of Action

Target Name Target Type Action Type Target ChEMBL ID
Thyroid hormone receptor PROTEIN COMPLEX AGONIST CHEMBL2111462

Unichem Links

Atlas triiodothyronine
SureChEMBL SCHEMBL8300
PharmGKB PA164778866
Human Metabolome Database HMDB0000265
DrugBank DB00279
PubChem: Thomson Pharma 14936961 14964754
PubChem 5920 7048703
NMRShiftDB 60020610
LINCS LSM-3991
Nikkaji J85.948F
PDBe T3
BindingDB 18860
EPA CompTox Dashboard DTXSID8023216
DrugCentral 1585
Metabolights MTBLC533015 MTBLC18258
Brenda 220663 2069 24561 132769 62262 5480 12575 5223 66993 144156 101783 9030 10918
Rhea 533015
ChemicalBook CB8221269
Guide to Pharmacology 2634
rxnorm CYTOMEL LIOTHYRONINE TRIOSTAT LIOTHYRONINE SODIUM
KEGG Ligand C02465
ChEBI 18258 533015
ZINC ZINC000003830999