Linaclotide

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Molecule Structure

Scientific Name

Linaclotide

Description of the Drug

Linaclotide is a guanylate cyclase-C agonist used to treat constipation associated with irritable bowel syndrome or that is idiopathic in nature.

Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB08890

Brand Name(s)

Constella, Linzess

Company Owner(s)

Allergan Sales Llc, Mylan Pharmaceuticals Inc

Mechanism(s) Of Action

Target Name Target Type Action Type Target ChEMBL ID
Heat-stable enterotoxin receptor SINGLE PROTEIN AGONIST CHEMBL1795197

Unichem Links

SureChEMBL SCHEMBL13114620
DrugBank DB08890
PubChem: Thomson Pharma 17491264
PubChem 16158208
Nikkaji J3.220.720K
EPA CompTox Dashboard DTXSID90234256
DrugCentral 4622
rxnorm LINZESS LINACLOTIDE
ChEBI 68551