Levothyroxine
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Scientific Name
Levothyroxine
Description of the Drug
Levothyroxine is a synthetic T4 hormone used to treat hypothyroidism that can be used along with surgery and radioiodine therapy to manage thyrotropin-dependent well-differentiated thyroid cancer.
Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB00451
http://www.drugbank.ca/drugs/DB00451
Brand Name(s)
Not Available
Company Owner(s)
Provell Pharmaceuticals Llc, Institut Biochimique Sa (Ibsa), Abbvie Inc, Jerome Stevens Pharmaceuticals Inc, Mylan Pharmaceuticals Inc, Amneal Pharmaceuticals Llc, Allergan Sales Llc, Teva Pharmaceuticals Usa Inc, Fresenius Kabi Usa Llc, Lupin Inc
Mechanism(s) Of Action
| Target Name | Target Type | Action Type | Target ChEMBL ID |
|---|---|---|---|
| Thyroid hormone receptor | PROTEIN COMPLEX | AGONIST | CHEMBL2111462 |
Clinical Trial(s)
Unichem Links
| SureChEMBL | SCHEMBL23098 | |||||||||
| PharmGKB | PA450221 | |||||||||
| Human Metabolome Database | HMDB0000248 | |||||||||
| DrugBank | DB00451 | |||||||||
| PubChem: Thomson Pharma | 14889116 | 14791233 | ||||||||
| PubChem | 25201348 | 5819 | ||||||||
| NMRShiftDB | 60021387 | |||||||||
| LINCS | LSM-5447 | |||||||||
| Nikkaji | J4.118A | |||||||||
| PDBe | T44 | |||||||||
| BindingDB | 408980 | 50301375 | ||||||||
| EPA CompTox Dashboard | DTXSID8023214 | |||||||||
| DrugCentral | 2646 | |||||||||
| Metabolights | MTBLC58448 | MTBLC18332 | ||||||||
| Brenda | 22220 | 86895 | 3235 | 152009 | 52934 | 1380 | ||||
| Rhea | 58448 | |||||||||
| ChemicalBook | CB5853720 | CB82551184 | ||||||||
| Guide to Pharmacology | 2635 | |||||||||
| rxnorm | LEVOXYL | LEVO-T | UNITHROID | THYRO-TABS | SYNTHROID | LEVOTHYROXINE SODIUM | LEVOTHROID | TIROSINT | LEVOTHYROXINE | EUTHYROX |
| KEGG Ligand | C01829 | |||||||||
| ChEBI | 58448 | 18332 | ||||||||
| ZINC | ZINC000003830993 |
