Levoketoconazole
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Scientific Name
Levoketoconazole
Description of the Drug
Levoketoconazole is one of two enantiomeric forms of racemic ketoconazole that strongly inhibits multiple steroidogenic enzymes and is used for the symptomatic treatment of endogenous Cushing’s syndrome.
Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB05667
http://www.drugbank.ca/drugs/DB05667
Brand Name(s)
Extina, Ketosidin, Ketozole, Nizoral, Nizoral A-D, Panfungol, Recorlev, Xolegel
Company Owner(s)
Strongbridge Dublin Ltd
Mechanism(s) Of Action
Target Name | Target Type | Action Type | Target ChEMBL ID |
---|---|---|---|
Cytochrome P450 11B2 | SINGLE PROTEIN | INHIBITOR | CHEMBL2722 |
Cytochrome P450 11B1 | SINGLE PROTEIN | INHIBITOR | CHEMBL1908 |
Cytochrome P450 11A1 | SINGLE PROTEIN | INHIBITOR | CHEMBL2033 |
Cytochrome P450 17A1 | SINGLE PROTEIN | INHIBITOR | CHEMBL3522 |
Clinical Trial(s)
Unichem Links
SureChEMBL | SCHEMBL41473 | ||
PharmGKB | PA450146 | ||
Human Metabolome Database | HMDB0012242 | ||
DrugBank | DB05667 | ||
PubChem: Thomson Pharma | 16774807 | ||
PubChem | 47576 | ||
NMRShiftDB | 60058702 | ||
Nikkaji | J301.870I | ||
PDBe | KLN | ||
BindingDB | 31768 | ||
EPA CompTox Dashboard | DTXSID60161949 | ||
Brenda | 6739 | 69472 | |
Rhea | 47518 | ||
rxnorm | EXTINA | NIZORAL | XOLEGEL |
PubChem: Drugs of the Future | 12013789 | ||
ChEBI | 47518 | ||
ZINC | ZINC000000643153 |