Leflunomide
Back to searchMolecule Structure
Scientific Name
Leflunomide
Description of the Drug
Leflunomide is a pyrimidine synthesis inhibitor indicated to treat rheumatoid arthritis.
Source: DrugBank Online – DrugBank.com. Retrieved 2023-02-07 from
http://www.drugbank.ca/drugs/DB01097
http://www.drugbank.ca/drugs/DB01097
Brand Name(s)
Arava, Leflunomide
Company Owner(s)
Fosun Pharma Usa Inc, Zydus Worldwide Dmcc, Barr Laboratories Inc, Sandoz Inc, Teva Pharmaceuticals Usa, Aet Pharma Us Inc, Heritage Pharmaceuticals Inc, Sanofi Aventis Us Llc, Abhai Llc, Lupin Ltd
Mechanism(s) Of Action
| Target Name | Target Type | Action Type | Target ChEMBL ID |
|---|---|---|---|
| Dihydroorotate dehydrogenase | SINGLE PROTEIN | INHIBITOR | CHEMBL1966 |
Clinical Trial(s)
Unichem Links
| SureChEMBL | SCHEMBL5057 | |||
| PharmGKB | PA450192 | |||
| Human Metabolome Database | HMDB0015229 | |||
| WDI | DR9800828 | DR9709821 | LEFLUNOMI | DR9800827 |
| DrugBank | DB01097 | |||
| PubChem: Thomson Pharma | 15221872 | |||
| PubChem | 3899 | |||
| Mcule | MCULE-9490869974 | |||
| LINCS | LSM-3771 | |||
| Nikkaji | J227.599F | |||
| BindingDB | 50054601 | |||
| EPA CompTox Dashboard | DTXSID9023201 | |||
| DrugCentral | 1552 | |||
| Brenda | 223559 | 229793 | ||
| ChemicalBook | CB1367708 | |||
| Guide to Pharmacology | 6825 | |||
| GSRS | 22bc23d2-549d-4acc-8d43-5cd833b56556 | |||
| rxnorm | LEFLUNOMIDE | ARAVA | ||
| PubChem: Drugs of the Future | 12013774 | |||
| KEGG Ligand | C07905 | |||
| ChEBI | 6402 | |||
| ZINC | ZINC000000004840 |
