Leflunomide

Back to search

Molecule Structure

Scientific Name

Leflunomide

Description of the Drug

Leflunomide is a pyrimidine synthesis inhibitor indicated to treat rheumatoid arthritis.

Source: DrugBank Online – DrugBank.com. Retrieved 2023-02-07 from
http://www.drugbank.ca/drugs/DB01097

Brand Name(s)

Arava, Leflunomide

Company Owner(s)

Fosun Pharma Usa Inc, Zydus Worldwide Dmcc, Barr Laboratories Inc, Sandoz Inc, Teva Pharmaceuticals Usa, Aet Pharma Us Inc, Heritage Pharmaceuticals Inc, Sanofi Aventis Us Llc, Abhai Llc, Lupin Ltd

Mechanism(s) Of Action

Target Name Target Type Action Type Target ChEMBL ID
Dihydroorotate dehydrogenase SINGLE PROTEIN INHIBITOR CHEMBL1966

Unichem Links

SureChEMBL SCHEMBL5057
PharmGKB PA450192
Human Metabolome Database HMDB0015229
WDI DR9800828 DR9709821 LEFLUNOMI DR9800827
DrugBank DB01097
PubChem: Thomson Pharma 15221872
PubChem 3899
Mcule MCULE-9490869974
LINCS LSM-3771
Nikkaji J227.599F
BindingDB 50054601
EPA CompTox Dashboard DTXSID9023201
DrugCentral 1552
Brenda 223559 229793
ChemicalBook CB1367708
Guide to Pharmacology 6825
GSRS 22bc23d2-549d-4acc-8d43-5cd833b56556
rxnorm LEFLUNOMIDE ARAVA
PubChem: Drugs of the Future 12013774
KEGG Ligand C07905
ChEBI 6402
ZINC ZINC000000004840