Leflunomide
Back to searchMolecule Structure
Scientific Name
Leflunomide
Description of the Drug
Leflunomide is a pyrimidine synthesis inhibitor indicated to treat rheumatoid arthritis.
Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB01097
http://www.drugbank.ca/drugs/DB01097
Brand Name(s)
Arava, Leflunomide
Company Owner(s)
Abhai Llc, Alembic Pharmaceuticals Ltd, Apotex Inc Etobicoke Site, Sandoz Inc, Wanbang Biopharmaceuticals, Aurobindo Pharma Ltd, Barr Laboratories Inc, Teva Pharmaceuticals Usa, Heritage Pharmaceuticals Inc Dba Avet Pharmaceuticals Inc, Sanofi Aventis Us Llc
Mechanism(s) Of Action
| Target Name | Target Type | Action Type | Target ChEMBL ID |
|---|---|---|---|
| Dihydroorotate dehydrogenase | SINGLE PROTEIN | INHIBITOR | CHEMBL1966 |
Clinical Trial(s)
Unichem Links
| SureChEMBL | SCHEMBL5057 | |
| PharmGKB | PA450192 | |
| Human Metabolome Database | HMDB0015229 | |
| DrugBank | DB01097 | |
| PubChem: Thomson Pharma | 15221872 | |
| PubChem | 3899 | |
| Mcule | MCULE-9490869974 | |
| LINCS | LSM-3771 | |
| Nikkaji | J227.599F | |
| BindingDB | 50054601 | |
| EPA CompTox Dashboard | DTXSID9023201 | |
| DrugCentral | 1552 | |
| Brenda | 223559 | 8448 |
| ChemicalBook | CB1367708 | |
| Guide to Pharmacology | 6825 | |
| rxnorm | ARAVA | LEFLUNOMIDE |
| PubChem: Drugs of the Future | 12013774 | |
| KEGG Ligand | C07905 | |
| ChEBI | 6402 | |
| ZINC | ZINC000000004840 |
