Scientific Name: Ixazomib
Brand Name: Ninlaro
Company Owner: Not Available
Mechanism Of Action Ixazomib is an N-capped dipeptidyl leucine boronic acid which reversibly inhibits the CT-L proteolytic (β5) site of the 20S proteasome. At higher concentrations, ixazomib also seems to inhibit the proteolytic β1 and β2 subunits and to induce accumulation of ubiquitinated proteins.
Description of the Drug: Ixazomib is a monoclonal antibody used with other medications to treat multiple myeloma in patients who have received one other therapy already.
Protein Data Bank:
Source: DrugBank Online – DrugBank.com. Retrieved 2023-01-23 from https://go.drugbank.com/drugs/DB09570