Ivabradine

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Molecule Structure

Scientific Name

Ivabradine

Description of the Drug

Ivabradine is a HCN channel blocker used to reduce the risk of hospitalization for worsening heart failure in adult patients and for treatment of stable symptomatic heart failure as a result of dilated cardiomyopathy in pediatric patients.

Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB09083

Brand Name(s)

Corlanor, Procoralan

Company Owner(s)

Amgen Inc, Centaur Pharmaceuticals Pvt Ltd

Mechanism(s) Of Action

Target Name Target Type Action Type Target ChEMBL ID
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 SINGLE PROTEIN BLOCKER CHEMBL1250417

Unichem Links

SureChEMBL SCHEMBL23472
PharmGKB PA166123415
DrugBank DB09083
PubChem: Thomson Pharma 14858507 14809487
PubChem 132999
Nikkaji J582.018I
BindingDB 50326992
EPA CompTox Dashboard DTXSID2048240
DrugCentral 3312
ChemicalBook CB41178988
Guide to Pharmacology 2357
rxnorm CORLANOR IVABRADINE HYDROCHLORIDE IVABRADINE
ChEBI 85966
ZINC ZINC000003805768