Irinotecan

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Molecule Structure

Scientific Name

Irinotecan

Description of the Drug

Irinotecan is an antineoplastic enzyme inhibitor used to treat metastatic carcinoma of the colon or rectum.

Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB00762

Brand Name(s)

Not Available

Company Owner(s)

Cipla Ltd, Picket Pharmaceuticals Inc, Ipsen Biopharmaceuticals Inc, Jiangsu Hengrui Pharmaceuticals Co Ltd, Emcure Pharmaceuticals Ltd, Akorn Operating Co Llc, Fresenius Kabi Usa Llc, Hospira Inc, Pliva Lachema As, Novast Laboratories Ltd

Mechanism(s) Of Action

Target Name Target Type Action Type Target ChEMBL ID
DNA topoisomerase I SINGLE PROTEIN INHIBITOR CHEMBL1781

Unichem Links

SureChEMBL SCHEMBL4034
PharmGKB PA450085
Human Metabolome Database HMDB0014900
DrugBank DB00762
PubChem: Thomson Pharma 14764625 14911520
PubChem 60838
Mcule MCULE-1702653278
LINCS LSM-2167
Nikkaji J261.801J
PDBe CP0
BindingDB 50128267
EPA CompTox Dashboard DTXSID1041051
DrugCentral 1482
Brenda 14217 229543 4670 159474 17312 25961 161387 20080 31924 139378 229542
ChemicalBook CB1124156
Guide to Pharmacology 6823
rxnorm IRINOTECAN HYDROCHLORIDE IRINOTECAN CAMPTOSAR ONIVYDE
KEGG Ligand C16641
ChEBI 80630
ZINC ZINC000001612996