Irinotecan
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Scientific Name
Irinotecan
Description of the Drug
Irinotecan is an antineoplastic enzyme inhibitor used to treat metastatic carcinoma of the colon or rectum.
Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB00762
http://www.drugbank.ca/drugs/DB00762
Brand Name(s)
Not Available
Company Owner(s)
Cipla Ltd, Picket Pharmaceuticals Inc, Ipsen Biopharmaceuticals Inc, Jiangsu Hengrui Pharmaceuticals Co Ltd, Emcure Pharmaceuticals Ltd, Akorn Operating Co Llc, Fresenius Kabi Usa Llc, Hospira Inc, Pliva Lachema As, Novast Laboratories Ltd
Mechanism(s) Of Action
Target Name | Target Type | Action Type | Target ChEMBL ID |
---|---|---|---|
DNA topoisomerase I | SINGLE PROTEIN | INHIBITOR | CHEMBL1781 |
Clinical Trial(s)
Unichem Links
SureChEMBL | SCHEMBL4034 | ||||||||||
PharmGKB | PA450085 | ||||||||||
Human Metabolome Database | HMDB0014900 | ||||||||||
DrugBank | DB00762 | ||||||||||
PubChem: Thomson Pharma | 14764625 | 14911520 | |||||||||
PubChem | 60838 | ||||||||||
Mcule | MCULE-1702653278 | ||||||||||
LINCS | LSM-2167 | ||||||||||
Nikkaji | J261.801J | ||||||||||
PDBe | CP0 | ||||||||||
BindingDB | 50128267 | ||||||||||
EPA CompTox Dashboard | DTXSID1041051 | ||||||||||
DrugCentral | 1482 | ||||||||||
Brenda | 14217 | 229543 | 4670 | 159474 | 17312 | 25961 | 161387 | 20080 | 31924 | 139378 | 229542 |
ChemicalBook | CB1124156 | ||||||||||
Guide to Pharmacology | 6823 | ||||||||||
rxnorm | IRINOTECAN HYDROCHLORIDE | IRINOTECAN | CAMPTOSAR | ONIVYDE | |||||||
KEGG Ligand | C16641 | ||||||||||
ChEBI | 80630 | ||||||||||
ZINC | ZINC000001612996 |