Indomethacin
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Scientific Name
Indomethacin
Description of the Drug
Indomethacin is a nonsteroidal anti-inflammatory (NSAID) used for symptomatic management of chronic musculoskeletal pain conditions and to induce closure of a hemodynamically significant patent ductus arteriosus in premature infants.
http://www.drugbank.ca/drugs/DB00328
Brand Name(s)
Artracin, Artracin sr, Berlind 75 ret, Flexin-25 continus, Flexin-50 continus, Flexin-75 continus, Imbrilon, Indocid-r, Indocid ret, Indocin, Indocin sr, Indoderm, Indoflex, Indolar, Indolar sr, Indo-lemmon, Indomax-25, Indomax-75 sr, Indomethacin, Indomod, Indo-paed, Indoptol, Indotard mr 75, Ledmecin, Maximet sr, Mobilan, Pardelprin mr, Rheumacin la, Rimacid, Slo-indo, Tivorbex
Company Owner(s)
Egalet Us Inc, Jubilant Generics Ltd, Sun Pharmaceutical Industries Inc, Halsey Drug Co Inc, Watson Laboratories Inc, Genus Lifesciences Inc, Heritage Pharmaceuticals Inc Dba Avet Pharmaceuticals Inc, Ivax Pharmaceuticals Inc Sub Teva Pharmaceuticals Usa, Able Laboratories Inc, Zydus Pharmaceuticals Usa Inc
Mechanism(s) Of Action
| Target Name | Target Type | Action Type | Target ChEMBL ID |
|---|---|---|---|
| Cyclooxygenase | PROTEIN FAMILY | INHIBITOR | CHEMBL2094253 |
Clinical Trial(s)
Unichem Links
| Atlas | indometacin | indomethacin | ||
| SureChEMBL | SCHEMBL9300 | |||
| PharmGKB | PA449982 | |||
| Human Metabolome Database | HMDB0014473 | |||
| DrugBank | DB00328 | |||
| PubChem: Thomson Pharma | 14754602 | |||
| PubChem | 3715 | |||
| Mcule | MCULE-5636486088 | |||
| NMRShiftDB | 20208999 | |||
| LINCS | LSM-3275 | |||
| Nikkaji | J1.368D | |||
| PDBe | IMN | |||
| BindingDB | 17638 | |||
| EPA CompTox Dashboard | DTXSID9020740 | |||
| DrugCentral | 1440 | |||
| Metabolights | MTBLC49662 | |||
| Brenda | 98002 | 546 | 125887 | 127068 |
| ChemicalBook | CB1750267 | |||
| Guide to Pharmacology | 1909 | |||
| rxnorm | INDOMETHACIN SODIUM | INDOCIN | INDOMETHACIN | TIVORBEX |
| KEGG Ligand | C01926 | |||
| ChEBI | 49662 | |||
| ZINC | ZINC000000601283 |
